Copper-mediated pyrazole synthesis from 2,3-allenoates or 2-alkynoates, amines and nitriles.
نویسندگان
چکیده
An efficient copper-mediated three-component reaction of 2,3-allenoates or 2-alkynoates, amines, and nitriles affording fully substituted pyrazoles with a very nice diversity has been developed. A tandem conjugate addition, 1,2-addition, and N-N bond formation mechanism has been proposed for this diverse synthesis of pyrazoles based on mechanistic studies.
منابع مشابه
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عنوان ژورنال:
- Chemical communications
دوره 50 57 شماره
صفحات -
تاریخ انتشار 2014